LETTERS TO THE EDITOR RE : RESIDUAL CONFOUNDING In
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چکیده
This dictionary, sponsored by the International Epidemiological Association, is due for revision, and we propose that this definition should be revised. It is unclear from the definition as currently worded how residual confounding differs from just confounding. Kleinbaum et al. (2) refer to residual confounding as both the lack of proper covariates and the effect of not sufficiently detailed information. It seems to us more appropriate to define residual confounding as the confounding which remains after unsuccessful attempts to adjust for it. The sources of residual confounding would then be both insufficiently detailed information (also stemming from improper categorization) and misclassification of the variable. Marshall and Hastrup (3) suggest the term "resonance" for the latter situation, which we do not find appealing. Following our suggestion, residual confounding becomes a variable-specific concept, as opposed to both variableand model-specific concepts. A more specific concept is needed to convey the fact that we only rarely have the information needed to fully adjust for confounding. A word is needed to describe the difference between theoretical effect estimates after complete confounder control and the empirical effect estimates after our attempts to control. "Residual confounding" could serve this purpose.
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تاریخ انتشار 2005